IGF-1 IN LEARNING & MEMORY

There is an ample amount of research indicating that Insulin-like growth factor-1 plays a role in cognitive decline. IGF-1 surges during the pubertal period and declines throughout adulthood and is drastically reduced in advanced age. In the Ashpole lab, we hope to understand how IGF-1 promotes learning and memory in adulthood and advanced age using transgenic mouse models. 

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Techniques

• Transgenic Mouse Model

• Stereotaxic Surgery

• Osmotic Pump Implantation

• Western Blot

• Golgi-Cox Stain

• Primary Cell Culture

• Microscopy

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